產品型號:K106653P
更新時間:2022-08-15
廠商性質:生產廠家
訪 問 量 :994
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產品分類
Anti-Smad4 Polyclonal Antibody
英文名稱 | Anti-Smad4 Polyclonal Antibody |
---|---|
宿主 | Rabbit |
別名 | DPC4;MADH4;Hsmad4;MAD homolog 4 |
應用 | IHC |
稀釋比例 | IHC 1:50-200. |
交叉反應 | Mouse |
蛋白分子量 | 60kDa |
Gene ID | 4089 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
純化方法 | Affinity purification |
亞型 | IgG |
免疫原 | A synthetic peptide of human Smad4 |
性狀 | 液體 |
Public Immunogen Range | A synthetic peptide of human Smad4 |
Subcellular Locations | Cytoplasm Nucleus |
Swiss Prot | Q13485 |
克隆類型 | Polyclonal Antibody |
背景資料 | In muscle physiology, plays a central role in the balance between atrophy and hypertrophy. When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4. MSTN decrease causes SMAD4 release and subsequent recruitment by the BMP pathway to promote hypertrophy via phosphorylated SMAD1/5/8. |