產品型號:K106572P
更新時間:2022-08-15
廠商性質:生產廠家
訪 問 量 :951
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產品分類
Anti-GAD65 Polyclonal Antibody
英文名稱 | Anti-GAD65 Polyclonal Antibody |
---|---|
宿主 | Rabbit |
別名 | GAD2;DCE2;MGC161605;MGC161607 |
應用 | WB IHC |
稀釋比例 | WB 1:2000-5000.IHC 1:50-200. |
交叉反應 | Human Mouse Rat |
蛋白分子量 | 65kDa |
Gene ID | 2572 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
純化方法 | Affinity purification |
亞型 | IgG |
免疫原 | A synthetic peptide of human GAD65 |
性狀 | 液體 |
Public Immunogen Range | A synthetic peptide of human GAD65 |
Subcellular Locations | Cytoplasm Cell membrane |
Swiss Prot | Q05329 |
克隆類型 | Polyclonal Antibody |
背景資料 | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. |
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