產品型號:K106558P
更新時間:2022-08-15
廠商性質:生產廠家
訪 問 量 :944
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產品分類
Anti-VEGFR1 Polyclonal Antibody
英文名稱 | Anti-VEGFR1 Polyclonal Antibody |
---|---|
宿主 | Rabbit |
別名 | Emrk2;Flt;Flt1;EC 2.7.10.1;Fms like tyrosine kinase 1 |
應用 | WB |
稀釋比例 | WB 1:3000. |
交叉反應 | Human Mouse Rat |
蛋白分子量 | 120kDa |
Gene ID | 14254 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
純化方法 | Affinity purification |
亞型 | IgG |
免疫原 | A synthetic peptide of human VEGFR1 |
性狀 | 液體 |
Public Immunogen Range | A synthetic peptide of human VEGFR1 |
Subcellular Locations | Cell membrane |
Swiss Prot | P35969 |
克隆類型 | Polyclonal Antibody |
背景資料 | VEGF Receptor 1 (also known as FLT) belongs to the src gene family and shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The protein acts as a receptor for VEGF, VEGFB and PGF. An alternatively spliced form of the gene produces a soluble protein (sFlt1) which binds vascular endothelial growth factor (VEGF) with high affinity. sFlt1 has a higher affinity for VEGF indicating that it may function as an inhibitor in the VEGF response. VEGF Receptor 1 is specifically expressed in most vascular endothelial cells and peripheral blood monocytes. |