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| 品牌 | SOLARBIO/索萊寶 | 貨號(hào) | K106473P |
|---|---|---|---|
| 規(guī)格 | 50ul/100ul | 供貨周期 | 現(xiàn)貨 |
| 主要用途 | WB | 應(yīng)用領(lǐng)域 | 醫(yī)療衛(wèi)生,環(huán)保,化工,生物產(chǎn)業(yè),農(nóng)林牧漁 |
Anti-IL12 Polyclonal Antibody
| 英文名稱(chēng) | Anti-IL12 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | IL-12A;CLMF p35;IL-12 subunit p35;NKSF1;IL12A |
| 應(yīng)用 | WB |
| 稀釋比例 | WB 1:3000. |
| 交叉反應(yīng) | Human Mouse Rat |
| 蛋白分子量 | 52kDa |
| Gene ID | 3592 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲(chǔ)存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human IL12 |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human IL12 |
| Subcellular Locations | Cell membrane Secreted |
| Swiss Prot | P29459 |
| 克隆類(lèi)型 | Polyclonal Antibody |
| 背景資料 | IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. |
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